No.
However, you can disable the button. Therefore you have to insert to your XML some lines of code as shown in the example below:
Example XML:
<customUI xmlns="http://schemas.microsoft.com/office/2006/01/customui"> <!-- Insert here --> <commands> <command idMso="Help" enabled="false"/> </commands> <!-- Here your code is going on --> <ribbon startFromScratch="false"> <tabs> <tab idMso="TabHomeAccess"> <group id="myGroup" label="My Group" insertBeforeMso="GroupViews"> <button id="myButton" label="My Button" imageMso="HappyFace"/> </group> <tab> </tabs> </ribbon> </customUI>